A team from the Mario Negri Institute for Pharmacological Research in Bergamo, Italy, which includes Greek-Cypriot biologist biologist Christoforos Xinaris, has made an important breakthrough in the engineering of new kidney tissue from a patient’s own cells.
The scientists created in their laboratories new kidney tissue that was integrated into the living organisms of mice and began working in the same manner as the original kidneys would including blood filtering and molecule re-absorption.
This new evolution in the field of lab-produced organic tissue gives scientists hope to better help patients in need of transplants. With the current worldwide shortage in transplants, Xinaris and his colleagues published their breakthrough research findings in the Journal of the American Society of Nephrology (JASN) paving the way for new researches in the field.
“The ability to build functional renal tissue starting from suspensions of single cells represents a considerable step toward the practical goal of engineering renal tissues suitable for transplantation and offers the methodological basis for a number of investigative and therapeutic applications,” said Xinaris, according to CyprusMail.com.
Xinaris was born in 1976 in the Republic of Cyprus and graduated from the Department of Biology of the University of Athens in 2001. Today he works at the Laboratory of Molecular Biology at Regenerative Medicine of the Department of Molecular Medicine of the Mario Negri Institute for Pharmacological Research.